February 3, 2020 Word for Word Media
Dr Carrie Minnaar informs us about hyperthermia, a new treatment in South Africa, and its benefits when used alongside chemotherapy and radiation. Hyperthermia explained Hyperthermia describes an increase in the tumour temperature above the normal physiological temperature range. A complex set of reactions ofĀ the tumour cells and environmentĀ in response to the heat results in improved tumour destruction.Ā  How does itĀ help? Possibly the most importantĀ response is the change in blood flowĀ to the tumour. In an attempt to lower the temperature at the tumour site,Ā the body responds by increasing the blood flow and oxygen to the heated area. While this may…

November 27, 2019 Word for Word Media
The careful handling and transport of chemotherapy drugs is fundamental to the treatment patients receive. We hear more about how Medipost Pharmacy gets this right. From the time an oncology practice places an order with the dispensing pharmacy until the moment it reaches the practice where it will be mixed and administered to patients, the highest level of care is required to ensureĀ that the right medicine reaches its destination safely, reliably, and in optimal condition.Ā  Supplier of choice Martie Duminy, a pharmacist at Hermanus Oncology, says that sheĀ has had an association of some six years’ standing with Medipost Pharmacy….

October 28, 2019 Word for Word Media

The three most common cancer treatments are surgery, chemotherapy and radiotherapy. These may be applied on their own or in a combination of one other. Icon Oncology takes a closer look at radiotherapy and its experience. Receiving radiation therapy Radiotherapy is a common form of therapeutic treatment that uses ionising radiation to eradicate or damage cancer cells. While the ideal situation is to cut the cancer out, it can be attached to the blood vessels and lymphatic tissue and this might not be possible. In this case, radiotherapy, which is a non-invasive treatment, might be recommended. Radiotherapy takes place at…

September 26, 2018 Word for Word Media
The chance of finding a matching bone marrow donor for a critically ill patient is just one in 100 000. But thanks to medical technology, shared international databases and the spirit of global cooperation, the SouthĀ African Bone Marrow Registry (SABMR) regularly finds that perfect match. For a child or adult with a life-threatening blood disease, like leukaemia, a bone marrow transplant can offer the greatest gift imaginable:Ā  a second chance at life.Ā  Bone marrow transplantation is unique medical work. It involves destroying an individual’s entire immune system and replacing it with one from somebody in the general population who’s…

June 1, 2018 Word for Word Media
We learn about the specialised and complicated allogeneic stem cell transplants. Allogeneic transplants – obtained from a donor Allogeneic transplants, also known as an allograft or donor peripheral blood stem cell transplant (PBSCT), differ from autologous transplants in that the stem cells are not obtained from the patient’s body but from a donor who may be related, or a matched unrelated donor (MUD). This type of transplant is much more specialised than an autologous transplant and a lotĀ more complicated. What diseases doĀ allogeneic transplants treat? Acute myeloblastic leukaemia; acute myelogenous leukaemia (AML) Chronic myelogenous leukaemia (CML) – this disease has…

March 26, 2018 Word for Word Media
Kate Paterson (31) recollects the days of her autologous stem cell transplant and high-dose chemotherapy. The first time I was allowed outside was a Sunday morning. The skeleton staff nurses delivered the results of my 2am blood tests without ceremony. I snuck a peek. My white cell count had been building slowly but fiercely from a flat 0 to a magnificent 1. This meant many things to me. I would be able to see the faces of my family again, no longer hidden behind masks. And, soon, I would be going home. But, at that moment, it meant I…

February 7, 2018 Word for Word Media

Any cancer diagnosis is traumatic and can cause confusion and anxiety, the team at the Ahmed Kathrada Cancer Institute have put together some guidelines to help you prepare as best as possible for your first oncology visit.

Before your appointment Bring someone with you – it is always good to have support, it will also help to have someone to make sense of everything that will be discussed. Draw up a list of your questions, often many concerns are forgotten while trying to absorb all the information from the appointment. During your appointment Questions to ask: What is…

February 7, 2018 Word for Word Media

An immuno-oncology drug, Pembrolizumab, recently received regulatory approval by the South African Health Products Regulatory Authority.Ā Dr Ronwyn van Eeden tells us more about the new drug.

Pembrolizumab has been registered in SA for two types of cancers. The first is a type of lung cancer, called non-small cell lung cancer. It’s registered for patients who have failed or Ā  Ā  progressed after initial treatment, such as chemotherapy. Usually the drug works better if the expression of PD-L1 (programmed cell death ligand-1) on the cancer is more than 51% as shown in clinical trials. The amount of PD-L1 on the…

February 7, 2018 Word for Word Media

Retired stem cell co-ordinator, Mary Farrell, explains the ins and outs of an autologous stem cell transplant.

What is an autologousĀ stem cell transplant? An autologous stem cell transplant is also known as high-dose chemotherapy with stem cell rescue. The word autologous (of cells and tissues) means obtained from the same individual. Not from a donor. The cells of the individual are collected in advance and stored. Then after high-dose chemotherapy is given to treat the underlying disease, the cells are returned to ā€˜rescue’ the patient’s bone marrow. What illnesses are autologous stem cell transplant used for? An autologous…