February 7, 2018 Word for Word Media

An immuno-oncology drug, Pembrolizumab, recently received regulatory approval by the South African Health Products Regulatory Authority.Ā Dr Ronwyn van Eeden tells us more about the new drug.

Pembrolizumab has been registered in SA for two types of cancers. The first is a type of lung cancer, called non-small cell lung cancer. It’s registered for patients who have failed or Ā  Ā  progressed after initial treatment, such as chemotherapy. Usually the drug works better if the expression of PD-L1 (programmed cell death ligand-1) on the cancer is more than 51% as shown in clinical trials. The amount of PD-L1 on the…

February 7, 2018 Word for Word Media

Retired stem cell co-ordinator, Mary Farrell, explains the ins and outs of an autologous stem cell transplant.

What is an autologousĀ stem cell transplant? An autologous stem cell transplant is also known as high-dose chemotherapy with stem cell rescue. The word autologous (of cells and tissues) means obtained from the same individual. Not from a donor. The cells of the individual are collected in advance and stored. Then after high-dose chemotherapy is given to treat the underlying disease, the cells are returned to ā€˜rescue’ the patient’s bone marrow. What illnesses are autologous stem cell transplant used for? An autologous…